Can I use a sapadm domain user in Windows ?

Yes!

In some cases it might be useful to configure sapadm as a domain user instead of a local user (for example, if you have multiple hosts with SAP Host Agent on each of them). If SAP Host Agent is already installed, uninstall it and then reinstall it again with the -user option by executing the following command:

saphostexec.exe -install -user <domain>\sapadm 

 

Note:

You need at least SAP Host Agent 7.20 PL 33 and the user must already exist in the domain!